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Who does not want to keep their mind active and stay young?
NATIONAL LIBRARY OF MEDICINE
Effect of oral resveratrol on the BDNF gene expression in the hippocampus of the rat brain.
Abstract
Resveratrol is a plant polyphenolic compound. Evidence indicates that resveratrol has beneficial effects against ageing and neurodegenerative diseases. The goal of our study was in vivo examination of the effects of resveratrol on the abundance of mRNA encoding Brain Derived Neurotrophic Factor (BDNF) in the hippocampus of rat brain. Rats were administrated orally by different doses (2.5-20 mg/kg bwt) of resveratrol for 3, 10 and 30 days. Saline was used as control and 10% ethanol in saline was used as vehicle for resveratrol. Measurement of BDNF mRNA by Real-time RT-PCR showed that levels of the mRNA for BDNF were significantly and dose dependently elevated in the hippocampal tissues of rats. The findings suggest that the neuroprotective effects of resveratrol may be at least partly due to its inducing effects on the expression levels of the BDNF mRNA.
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Yep, another drawing of the Japanese Knotweed Warrior by me, Sharon J. Bainbridge. I just cannot get enough of researching this amazing herbal plant! Now, back to my fun art day with my darling daughter ... Melody!
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